Главная → Новости, события, мероприятия, новые файлы и материалы, видео и статьи → В «Наука» добавлена «Chemometric analysis of bioimplants of bone tissues during their manufacture»

В «Наука» добавлена «Chemometric analysis of bioimplants of bone tissues during their manufacture»

01 января 2021 г.
Автор: Timchenko, P., Timchenko, E., Volova, L., Frolov, O.
Figure 1 – Averaged normalized Raman spectra of mineralized and demineralized samples of bioimplants, taken from cadaverous (1,4) and antemortem (2,3) bone tissue
Ii – intensity of spectral lines of the analyzing components.
Figure 2 – The graph of PCA counts of averaged Raman spectra of eight samples of bone tissue
Figure 3 – The graph of PCA loads of spectral lines of the Raman spectra of the samples of bone tissues
Figure 4 – Two-dimensional diagrams of the introduced coefficients: CB – Cadaveric without Ultrasound; CU – Cadaveric with Ultrasound; IB – Intravital without Ultrasound; IU – Intravital with Ultrasound

CHEMOMETRIC ANALYSIS OF BIOIMPLANTS OF BONE TISSUES DURING THEIR MANUFACTURE

P.E. Timchenkoa, E.V. Timchenko*a , L.T. Volovab, O.O. Frolova

aSamara National Research University, 34, Moskovskoye shosse, Samara, 443086, Russia 

bSamara State Medical University, 89 Chapayevskaya St., Samara, 443099, Russia

ABSTRACT

The results of expanded spectral analysis of donor bone implants using the Raman spectroscopy method are presented in the work. Mathematical methods of improving resolution of spectral contours and chemometric analysis are used for evaluation of component composition of the implants. It is shown that the Raman spectroscopy can be used for evaluation of relative concentration of mineral and organic components in extracellular matrix of bone tissue. Spectral features of the samples of bone tissues demineralized and processed with ultrasound with different degree are found as a result of the study. The criteria allowing evaluating the component composition during manufacture of bioimplants are suggested in the work.

Keywords: Raman spectroscopy, spectral analysis, bone bioimplants, chemometrics, demineralization, “Lioplast”.

Downloaded From: https://www.spiedigitallibrary.org/conference-proceedings-of-spie on 14 May 2020 Terms of Use: https://www.spiedigitallibrary.org/terms-of-use Tissue Optics and Photonics, edited by Valery V. Tuchin, Walter C. P. M. Blondel, Zeev Zalevsky, Proc. of SPIE Vol. 11363, 113632A · © 2020 SPIE CCC code: 0277-786X/20/$21 · doi: 10.1117/12.2565723 Proc. of SPIE Vol. 11363 113632A-1