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Analysis of the mineral component for cortical bone tissue by Raman spectroscopy after ovariectomy and its treatment with allogeneic hydroxyapatite

Статья

In the work results of experimental researches of mineral component of cortical tissue after ovariectomy and estimation of correction using allogeneic hydroxyapatite (HAP) by the method of Raman spectroscopy are presented. A comparative analysis of bone samples from non-ovariectomized and ovariectomized animals after HAP injection was carried out using the Raman spectra. Coefficients which allow to estimate resorption of cortical tissue after ovariectomy and correction using HAP was entered. Introduction of HAP suspension showed that the consequences of ovariectomy can be almost compensated for the cortical tissue. 

Ij is the intensity values on the wave numbers 957 cm-1 and 1069 cm-1 .
Raman spectra normelized to the average intensity value of the cortical tissue of the bones, where (a) ovariectomy, (b) non – ovariectomy with HAP; (c) ovariectomy with HAP.
Two – dimentional diagrams of the input coefficients, where the first group is ovariectomized, the second group is non-ovariectomized with HAP, and the third group is ovariectomized with HAP.
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