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Optical estimation of the composition of bone implants during processing

Статья

This paper presents the results of the experimental study of the use of ultrasonic treatment for the production of bone implants using Raman spectroscopy (RS). It shows that Raman spectroscopy can be used to estimate a change of bone implants composition during their processing. It was shown that ultrasonic treatment reduces the concentration of cellular components in the bone tissue. The conclusion was based on the two-dimensional analysis of the given ratios.

– Experimental stand : 1 – the object under study; 2 – Raman probe RPB-785; 3 – spectrometer Shamrock sr-303 i; 4 – built-in cooled camera DV420A-OE; 5 – computer; 6 – laser module LuxxMaster LML-785.0 RB-04; 7 – laser module power supply.
Raman spectra normalized to the average intensity value for: 1) demineralized bone tissue samples 2) mineralized bone tissue samples
Raman spectra normalized to the average intensity value for demineralized bone tissue samples: 1) without ultrasonic processing 2) with ultrasonic processing.
Two – dimentional diagrams of the input coefficients
where Ii – intensity values on wave numbers of analyzed components.
Raman bands for the samples of bone tissue
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